The series takes place 20 years after the events in Diya Aur Baati Hum and it revolves around the children of Sooraj and Sandhya, mainly focusing on their daughter, Kanak.
Kanak's grandmother, Santosh initially hates her to the core, blaming her to be the reason behind her parents, Sooraj and Sandhya's death. She fixes her alliance with Mayank who lives abroad in London. Kanak's life takes a new turn when Uma Shankar Toshniwal, a rich, kind-hearted and devotional, spiritual man of fath and an Ayurveda doctor by profession, marries her, believing that as a sign from Lord. Uma is a strong faithful believer in morals and ways from his own spirit but also sometimes wrongly guided by his greedy and hypocritical maternal aunt, Nanda. Kanak sets off on a journey with Uma to teach him the greatest moral of life – humanity. In the process, Kanak falls in love with Uma after establishing herself as the perfect wife for him. Uma's sister Saras and Kanak's brother Vansh elope, enabling Nanda to instigate Uma in hating Kanak. Kanak soon divorces Uma and demands 50% of his property which is named on Nanda. When Uma and Palomi are getting married, Uma feels that Kanak is in danger so he leaves his marriage and searches Kanak. He finds Kanak in a forest where Nanda's son Aditya hangs Kanak on a tree. He saves her life and sends Aditya to jail.
Uma and Kanak confess their love and decide to get married in ten days. Kanak exposes Nanda and Aditya in front of Uma when she gives poison to Laddus. Nanda then falsely accuses Uma for killing Palomi and gets him sentenced jailed for ten years. They both escape and go to Bangkok. They change their identity and expose Nanda and Aditya.
After returning to India, they soon decide to get married but Uma, for some unknown reason, marries Meera Mittal, the deranged daughter of a rich businessman, ditching Kanak.
2 years later
Kanak, now self-sufficient and possessing bitter hatred towards Uma, eventually reappears in his life, who has become a successful business tycoon running the 'K & U' company in the meantime. It is revealed later on that Uma still loves Kanak and was actually blackmailed and forced into marrying Meera to save his younger cousin Suman from receiving punishment for a murder she had inadvertently committed. Meera upon knowing Kanak's identity, along with Aditya, tries many heinous ways to separate the duo, including an unsuccessful attempt to marry off Kanak to Akshay also was hell-bent on ruining her. Suman is now full of guilt and decides to sacrifice her life so that Uma and Kanak can re-unite. They save her and the truth is finally unveiled before Kanak. She gets rid of her ill-feelings towards Uma and gets Meera arrested with the help of others by hatching a crafty plan.
They remarry after settling their differences and restore their relationship. Aditya realises his mistake and becomes loyal to his brother and sister-in-law. It is then that Nanda comes out of jail.
After Saras suffering an unfortunate miscarriage on account of failing to reach the medical facility on time, and seeing Uma's grief over the matter, Kanak and Aditya launch a bike ambulance service for Uma. This creates a number of enemies for Uma and Kanak from the very outset, and Dr. Parag, the corrupt Dean of Pratistha Medical College, joins hands with Nanda to cancel Uma's license so that he can use the idea to promote his own medical college and take the credit totally upon himself. Kanak decides to study paramedics and become a doctor herself to save the license from being cancelled and so that no one can label her as an amateur when she treats patients.
After facing numerous hurdles and hindrances set by the Dean himself at Dr. Parag's college, in an attempt to crush her dream, she finally succeeds in exposing Dr. Parag's true nature to the public. As a result, he is arrested and sentenced to imprisonment. It is revealed that during his time in jail, Nanda was subjected to ill-treatment by Dr. Parag, which fuels her desire for revenge upon her release. However, upon her release, she decides to abandon her plots against Uma and Kanak, choosing a different path.
Uma at this time receives a fake call and is attacked by goons, who also trash his bike ambulance. He recovers 6 months later, but loses his memory. To everyone's surprise, he turns into the same superstitious person he was before. He force Kanak to either choose him or pursue her paramedics course. Kanak ultimately chooses to continue her dream of becoming a doctor. Uma supports her decision, and Aditya then reveal that it was their plan all along to infuse some confidence and passion into Kanak, which she was lacking and also that he had never lost his memory. With this, the story finally ends on a happy note as Kanak sets off for her new career with the blessings of all the elders.